The adsorption characteristics of the alkaline nitride pyridine in simulated oil onto sixteen alkyl three methyl bromide(CTAB) modified SAPO-44 molecular sieve were studied. The effects of the amount of CTAB on the adsorption of basic nitrides on SAPO-44 zeolites were investigated. Moreover, the adsorption isotherms, kinetics and thermodynamics of the adsorption of alkaline nitrogen were studied. The results showed that when the amount of CTAB added was 0.06, the maximum equilibrium adsorption capacity reached 7.24 mg/g. The CTAB modified SAPO-44 molecular sieve has better adsorption efficiency when compared with the unmodified SAPO-44 molecular sieve. The adsorption isotherm of alkaline nitride on CTAB modified SAPO-44 molecular sieve is more in line with the Langmuir equation.The adsorption process accords with the pseudo second-order kinetic model, and the adsorption activation energy is 48.25 kJ/mol.